Mathias Rainer

Title: Innovations by Mathias Rainer: Pioneering Techniques in Protein Analysis

Introduction

Mathias Rainer, an inventive mind based in Innsbruck, Austria, has made significant contributions to the field of protein analysis through his innovative inventions. With a total of two patents to his name, Rainer focuses on groundbreaking methods to isolate phosphoproteins and glycoproteins, enhancing our understanding of biological samples.

Latest Patents

Rainer's latest patents showcase advanced methodologies for protein isolation. The first patent, titled "Isolation of phosphoproteins, glycoproteins and fragments thereof," introduces methods and apparatus for selectively isolating phosphorylated and glycosylated proteins along with their fragments. This innovation employs metal cations to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method is versatile and applicable to various biological samples including HeLa cells, food items, and human cerebrospinal fluid. The proteins are efficiently isolated, recovered, and readied for analysis through mass spectrometry or other analytical approaches, achieving detection limits as low as the femtomole level. This invention presents invaluable tools for protein analysis and diagnostics.

The second patent, "Pipette tip containing particle-filled polymer monolith," details a pipette tip designed with a porous organic monolith doped with active particles. Utilizing a unique polymerization method, these extraction tips maintain high permeability, allowing samples to effectively pass through the monolithic bed. This extraction tip stands out as an ideal instrument for solid-phase extraction, particularly for the desalting, isolation, and purification of biomolecules like peptides and proteins.

Career Highlights

Throughout his career, Mathias Rainer has continuously pushed the boundaries of protein analysis technology. His innovative approach towards understanding complex biological samples has established him as a key figure in his field. His patents not only reflect his ingenuity but also demonstrate his commitment to improving diagnostic techniques through scientific advancements.

Collaborations

Rainer has collaborated with distinguished colleagues such as Guenther Bonn and Douglas T Gjerde. These partnerships have played a significant role in enhancing his research and contributing to the successful development of his patented technologies.

Conclusion

Mathias Rainer's contributions to the field of protein analysis are marked by his innovative patents, which pave the way for enhanced diagnostic methods. With his focused research and collaborative efforts, Rainer continues to impact the scientific community, offering promising advancements in the isolation and analysis of biomolecules. His work stands as a testament to the potential of innovation in transforming scientific methodologies.