Company Filing History:
Years Active: 2015
Title: Masha Idelson: Innovator in Stem Cell Research
Introduction
Masha Idelson is a prominent inventor based in Maale Adumim, Israel. She has made significant contributions to the field of stem cell research, particularly in the differentiation of retinal pigment epithelial (RPE) cells. Her innovative work has the potential to impact treatments for various retinal diseases.
Latest Patents
Masha Idelson holds a patent for "Retinal pigment epithelial cells differentiated from embryonic stem cells with nicotinamide and activin A." This invention focuses on RPE cells that can be obtained through directed differentiation from stem cells, especially human stem cells. The research demonstrates that culturing stem cells in the presence of members of the TGFβ superfamily, such as Activin A, induces the differentiation into mature and functional RPE cells. The effectiveness of this method is evidenced by the expression of specific markers associated with mature RPE cells, including MiTF-A, RPE65, and Bestrophin. Additionally, the cells are cultured with nicotinamide, which enhances their response to the inductive effects of the TGFβ superfamily members. The patent also outlines methods for performing this directed differentiation and the applications of the resulting RPE cells.
Career Highlights
Masha Idelson is associated with Hadasit Medical Research Services and Development Ltd., where she continues her research and development efforts. Her work is recognized for its potential to advance medical treatments and improve patient outcomes in the field of ophthalmology.
Collaborations
Masha collaborates with notable colleagues, including Ruslana Alper-Pinus and Alex Obolensky. These partnerships enhance her research capabilities and contribute to the advancement of innovative solutions in stem cell therapy.
Conclusion
Masha Idelson's contributions to stem cell research, particularly in the differentiation of retinal pigment epithelial cells, highlight her role as an innovator in the medical field. Her patent and ongoing work at Hadasit Medical Research Services and Development Ltd. underscore her commitment to advancing healthcare solutions.