Company Filing History:
Years Active: 2011-2015
Title: Innovations by Masayuki Kai: Advancements in Thrombocytopenia Treatment
Introduction
Masayuki Kai is a notable inventor based in Gunma, Japan, recognized for his contributions to biotechnology, specifically in the field of therapeutic antibodies. With a focus on innovative solutions for medical challenges, he holds three patents that exemplify his commitment to advancing healthcare.
Latest Patents
One of Masayuki Kai's significant inventions is an agonist antibody to the human thrombopoietin receptor (human c-Mpl). This groundbreaking advancement provides pharmaceutical compositions designed for treating thrombocytopenia, a condition characterized by low platelet counts. The disclosed agonist antibody features (1) antibody constant regions that may include domain substitutions and modifications of amino acid residues, and (2) antibody variable regions that can bind to and activate the human thrombopoietin receptor. Impressively, the agonist antibody induces colony formation at concentrations of 10,000 ng/ml or lower and exhibits maximal activity at least 50% higher than that of PEG-rHuMGDF, with an effective concentration (EC50) of 100 nM or less.
Career Highlights
Masayuki Kai's work is primarily associated with Kyowa Hakko Kirin Co., Limited, where he has made significant strides in the field of therapeutics. His expertise in creating innovative antibodies has positively impacted research and development efforts aimed at enhancing patient treatment options.
Collaborations
Throughout his career, Masayuki has collaborated with esteemed colleagues, including Kazuhiro Motoki and Shiro Kataoka. These partnerships reflect a commitment to teamwork and innovation, fostering advancements in biotechnology that can benefit many patients worldwide.
Conclusion
Masayuki Kai stands out as a prominent inventor in the biotechnology sector, particularly for his work on agonist antibodies aimed at treating thrombocytopenia. His contributions not only demonstrate his innovation but also highlight the collaborative efforts within Kyowa Hakko Kirin Co., Limited. As he continues to push the boundaries of medical science, Masayuki Kai serves as an inspiration for future inventors in the field.