Company Filing History:
Years Active: 1991-1993
Title: Masami Fukuoka: Innovator in Antitumor Polypeptides
Introduction
Masami Fukuoka is a notable inventor based in Hino, Japan. She has made significant contributions to the field of biotechnology, particularly in the development of novel polypeptides with antitumor activity. With a total of 2 patents, her work has the potential to impact cancer treatment significantly.
Latest Patents
Fukuoka's latest patents include innovations related to tumor necrosis factor (TNF). One of her key inventions is a novel physiologically active polypeptide that exhibits antitumor activity. This polypeptide is derived from human TNF, with specific modifications that enhance its efficacy while reducing side effects, particularly cytotoxicity. The amino acid sequence of this polypeptide corresponds closely to that of human TNF, with the first ten amino acids deleted and additional modifications made to improve its therapeutic potential. Furthermore, her patents encompass a DNA fragment encoding the polypeptide, a recombinant plasmid, and methods for producing the polypeptide using transformed microorganisms.
Career Highlights
Masami Fukuoka is associated with Teijin Limited, a company known for its advancements in various technological fields. Her work at Teijin has allowed her to focus on innovative solutions in biotechnology, particularly in cancer research.
Collaborations
Fukuoka has collaborated with notable colleagues, including Satoshi Nakamura and Tsukio Masegi. These collaborations have contributed to her research and the development of her patented technologies.
Conclusion
Masami Fukuoka's contributions to the field of biotechnology, particularly in the development of antitumor polypeptides, highlight her innovative spirit and dedication to improving cancer treatment. Her work continues to pave the way for advancements in therapeutic options for patients.