Mt. Airy, MD, United States of America

Marzena Pazgier


Average Co-Inventor Count = 4.8

ph-index = 1

Forward Citations = 2(Granted Patents)


Company Filing History:


Years Active: 2018-2020

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2 patents (USPTO):Explore Patents

Title: Marzena Pazgier: Innovator in HIV Research

Introduction

Marzena Pazgier is a prominent inventor based in Mt. Airy, MD (US), known for her significant contributions to the field of HIV research. With a total of 2 patents, she has made strides in developing innovative immunogens aimed at combating HIV.

Latest Patents

Pazgier's latest patents include a stable immunogen based on the inner domain of HIV-1 gp120, which is designed to induce immunity against HIV. This patent focuses on stable immunogens that selectively present the gp120 C1/C2 region in its CD4-bound state within a minimal structure. These immunogens can be utilized for vaccinating subjects against HIV, the virus responsible for Acquired Immunodeficiency Syndrome (AIDS). Additionally, they can serve as targets in screening for small molecule or peptide inhibitors that block HIV-1 viral entry and attachment steps, as well as probes for identifying gp120 C1/C2 region-specific antibodies.

Another notable patent involves a recombinant fusion protein comprising HIV gp120 linked to an enhancing CD4 binding site monoclonal antibody. This innovation includes fusion proteins that consist of portions of the HIV-1 Env protein (gp120 and gp140) and single-chain fragment V regions (ScFv) of an enhancing antibody. These fusion proteins may be used in immunogenic formulations for vaccination against HIV-1 infection and methods for generating an immune response.

Career Highlights

Marzena Pazgier is affiliated with the University System of Maryland, where she continues her research and development efforts in the field of immunology and virology. Her work has been instrumental in advancing the understanding of HIV and developing potential vaccines.

Collaborations

Pazgier collaborates with notable colleagues, including George K Lewis and Yongjun Guan, who contribute to her research initiatives and help drive innovation in HIV-related studies.

Conclusion

Marzena Pazgier's contributions to HIV research through her patents and collaborations highlight her role as a leading inventor in the field. Her work aims to provide new avenues for vaccination and treatment against HIV, showcasing the importance of innovation in addressing global health challenges.

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