Company Filing History:
Years Active: 2001
Title: The Innovative Contributions of Maryanne J Little
Introduction
Maryanne J Little is a prominent inventor based in Groton, MA (US). She has made significant contributions to the field of nucleic acid sequencing through her innovative patent. Her work exemplifies the intersection of biotechnology and analytical chemistry.
Latest Patents
Maryanne J Little holds a patent for "Mass spectrometric methods for sequencing nucleic acids." This patent describes a mass spectrometric method that utilizes RNA polymerases, including both DNA-dependent and RNA-dependent RNA polymerases. The method employs a modified Sanger sequencing strategy, generating a set of nested RNA transcripts through base-specific chain termination. These transcripts are then analyzed using mass spectrometry. Additionally, the patent provides a method for identifying transcriptional terminator sequences or attenuator sequences.
Career Highlights
Maryanne J Little has established herself as a key figure in her field, working at Sequenom, Inc. Her innovative approach to nucleic acid sequencing has paved the way for advancements in genetic research and diagnostics. With her expertise, she has contributed to the development of more efficient and accurate sequencing methods.
Collaborations
Maryanne has collaborated with notable colleagues, including Changwon Kang and Young-Soo Kwon. Their combined efforts have further enhanced the research and development of mass spectrometric techniques in the field of molecular biology.
Conclusion
Maryanne J Little's contributions to the field of nucleic acid sequencing through her innovative patent highlight her role as a leading inventor. Her work continues to influence advancements in biotechnology and molecular research.