Company Filing History:
Years Active: 2023
Title: Mary-Ann Siegert: Innovator in Biochemistry
Introduction: Mary-Ann Siegert is a notable inventor based in Berlin, Germany. With a keen focus on biochemistry, she has made significant contributions to the field through her innovative research and patented inventions.
Latest Patents: Mary-Ann Siegert holds a patent for the "Synthesis of (2S,3R,4R)-4,5-dihydroxyisoleucine and derivatives." This invention involves a sophisticated method for preparing a 4,5-dihydroxyisoleucine derivative. The process includes an asymmetric Claisen rearrangement of a Z-aminocrotyl-glycin ester, followed by the kinetic resolution of the product diastereomer mix by acylase. The final step involves the Sharpless dihydroxylation of the resulting 2-amino-3-methylpent-4-enoic acid derivative, showcasing her expertise in complex organic synthesis.
Career Highlights: Mary-Ann is currently associated with Heidelberg Pharma Research GmbH, where her contributions extend beyond individual projects. Her work not only enhances her career but also drives innovation in drug research and development.
Collaborations: Throughout her career, Mary-Ann has collaborated with talented researchers, including Caroline Knittel and Roderich Süssmuth. These collaborations have played a pivotal role in advancing her research and developing innovative solutions in the field of biochemistry.
Conclusion: Mary-Ann Siegert exemplifies the spirit of innovation with her patent in biochemical synthesis. Her work at Heidelberg Pharma Research GmbH, combined with her collaborations, positions her as a significant contributor to modern scientific advancements. Through her inventions, she continues to inspire future generations of inventors and scientists.