Company Filing History:
Years Active: 2020
Title: Martina Tepla: Innovator in Antitumor Compositions
Introduction
Martina Tepla is a notable inventor based in Policka, Czech Republic. She has made significant contributions to the field of medical science, particularly in the development of antitumor compositions. Her innovative work focuses on utilizing hyaluronic acid and inorganic nanoparticles to create effective treatments for various types of cancer.
Latest Patents
Martina Tepla holds a patent for an antitumor composition based on hydrophobized hyaluronan and inorganic nanoparticles stabilized by oleic acid. This invention relates to a composition that serves as a carrier for inorganic nanoparticles, which may include superparamagnetic nanoparticles, ZnO nanoparticles, and upconversion nanoparticles. The composition has shown selective cytotoxicity against both suspension and adherent tumor cell lines, particularly those associated with colorectal carcinoma, lung carcinoma, hepatocellular carcinoma, and breast adenocarcinoma. The highest cytotoxic effects were observed with the composition based on an oleyl derivative of hyaluronan combined with SPIONs. Additionally, this composition can be used for in vivo detection of accumulation in the body, especially in tumors or the liver, and is sterilizable in its final package.
Career Highlights
Martina Tepla is currently associated with Contipro A.S., where she continues her research and development in innovative medical solutions. Her work has positioned her as a key figure in the field of nanomedicine, contributing to advancements that may improve cancer treatment outcomes.
Collaborations
Some of her notable coworkers include Daniela Smejkalova and Kristina Nesporova, who collaborate with her on various research projects aimed at enhancing the efficacy of antitumor therapies.
Conclusion
Martina Tepla's contributions to the field of antitumor compositions highlight her innovative spirit and dedication to improving cancer treatment. Her work exemplifies the potential of combining nanotechnology with medical science to create effective therapeutic solutions.