Company Filing History:
Years Active: 2009-2014
Title: Martin Woodle: Innovator in RNA Therapeutics
Introduction
Martin Woodle is a prominent inventor based in Bethesda, MD (US), known for his significant contributions to the field of RNA therapeutics. With a total of 7 patents, he has focused on developing innovative solutions for treating various viral infections and diseases involving unwanted neovascularization.
Latest Patents
One of his latest patents is titled "Compositions for treating respiratory viral infections and their use." This invention provides siRNA compositions that interfere with viral replication in respiratory viral infections, including respiratory syncytial virus and avian influenza A, including the H5N1 strain. The invention further details the use of these siRNA compositions to inhibit the expression of viral genes in infected cells, offering potential treatments for respiratory virus infections. The polynucleotide described in this patent includes a first nucleotide sequence of 15 to 30 bases that targets the genome of respiratory syncytial virus or influenza A virus, along with complementary sequences and various forms of polynucleotides.
Another notable patent is "Composition and methods of RNAi therapeutics for treatment of cancer and other neovascularization diseases." This invention provides compositions and methods for treating diseases characterized by unwanted neovascularization. It focuses on controlling neovascularization through selective inhibition of pro-angiogenic biochemical pathways, including the inhibition of VEGF pathway gene expression. The nanoparticle compositions developed can be used alone or in combination with other therapeutic agents, targeting diseases such as cancer, ocular disease, arthritis, and inflammatory diseases.
Career Highlights
Throughout his career, Martin Woodle has worked with several notable companies, including Intradigm Corporation and Sirnaomics, Inc. His work has significantly advanced the field of RNA therapeutics, leading to innovative treatments that address critical health challenges.
Collaborations
Martin has collaborated with esteemed colleagues such as Patrick Y Lu and Yijia Liu, contributing to the development of groundbreaking therapeutic solutions.
Conclusion
Martin Woodle's innovative work in RNA therapeutics has made a substantial impact on the treatment of viral infections and neovascularization diseases. His patents reflect a commitment to advancing medical science and improving patient outcomes.