Markus W Covert

Title: Innovations of Markus W. Covert

Introduction

Markus W. Covert is a prominent inventor based in San Diego, CA. He has made significant contributions to the field of human metabolic modeling and biosystem reaction networks. With a total of 3 patents, his work focuses on advancing our understanding of physiological functions through innovative methodologies.

Latest Patents

One of Covert's latest patents is titled "Human metabolic models and methods." This invention provides in silico models for determining the physiological function of human cells, including human skeletal muscle cells. The models incorporate a data structure that relates a plurality of reactants to a plurality of reactions, along with a constraint set for these reactions. Additionally, the invention includes commands for determining a distribution of flux through the reactions that predict physiological function. A model can also feature a gene database containing information about associated genes. Furthermore, the invention outlines methods for creating an in silico model and for determining physiological functions using this model.

Another significant patent is "Methods and systems to identify operational reaction pathways." This invention offers a method for refining a biosystem reaction network. The process involves providing a mathematical representation of a biosystem, reconciling this representation, and determining differences between observed behavior and in silico behavior under similar conditions. The method also includes modifying the structure of the mathematical representation and assessing the differences in behavior post-modification.

Career Highlights

Markus W. Covert has worked with esteemed institutions such as the University of California and Genomatica, Inc. His research and innovations have played a crucial role in enhancing our understanding of metabolic processes and biosystem dynamics.

Collaborations

Covert has collaborated with notable colleagues, including Bernhard O. Palsson and Markus Herrgard. These partnerships have contributed to the advancement of research in metabolic modeling and biosystems.

Conclusion

Markus W. Covert's innovative work in human metabolic models and biosystem reaction pathways showcases his dedication to advancing scientific knowledge. His contributions continue to influence the fields of biology and biotechnology.