Schwetzingen, Germany

Markus Grosse


Average Co-Inventor Count = 4.6

ph-index = 2

Forward Citations = 5(Granted Patents)


Location History:

  • Ludwigsh, DE (2004)
  • Schwetzingen, DE (2006 - 2009)

Company Filing History:


Years Active: 2004-2009

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3 patents (USPTO):Explore Patents

Title: Innovations of Inventor Markus Grosse

Introduction

Markus Grosse is a notable inventor based in Schwetzingen, Germany. He has made significant contributions to the field of chemistry, particularly in the production of biperiden. With a total of three patents to his name, Grosse's work showcases his expertise and innovative spirit.

Latest Patents

One of Grosse's latest patents is a method for producing biperiden IV. This invention involves reacting exo-1-(bi-cyclo[2.2.1]hept-5-en-2-yl)-3-piperidino-1-propanone with a phenylmagnesium compound. The process allows for the efficient synthesis of biperiden, which is valuable in medicinal chemistry. Another significant patent is a method for the production of biperiden, which details the reaction of an exo/endo mixture of 1-(bi-cyclo[2.2.1]hept-5-en-2-yl)-3-piperidino-1-propanone with a phenyl magnesium compound. This method results in an isomer mixture that can be converted into biperiden hydrochloride, followed by isolation and crystallization of the free base.

Career Highlights

Throughout his career, Markus Grosse has worked with prominent companies, including Abbott GmbH & Co. KG and Abbott GmbH & Co. DG. His experience in these organizations has contributed to his development as an inventor and has provided him with valuable insights into the pharmaceutical industry.

Collaborations

Grosse has collaborated with several professionals in his field, including Peter Klein and Marco Thyes. These partnerships have likely enhanced his research and development efforts, leading to innovative solutions in his work.

Conclusion

Markus Grosse's contributions to the field of chemistry, particularly through his patents related to biperiden, highlight his innovative capabilities. His career and collaborations reflect a commitment to advancing pharmaceutical science.

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