This inventor holds 2 USPTO granted patents and 1 published patent application and 1 EPO patent. Top assignees: Licentia Oy, Orion Diagnostica Oy. Active years: 2007-2011.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2007-2011
Title: Innovations of Markku Sakari Kulomaa
Introduction
Markku Sakari Kulomaa is a notable inventor based in Tampere, Finland. He has made significant contributions to the field of biochemistry, particularly through his innovative work on avidin proteins. With a total of 2 patents, Kulomaa's inventions have the potential to impact various applications in biotechnology.
Latest Patents
Kulomaa's latest patents include advancements in avidin mutants. One of his notable inventions involves the design of two circularly permuted avidin monomers. These monomers are fused to create a pseudo-tetrameric dual-chain avidin, known as dcAvd, which retains biological activity in biotin binding. This innovation allows for the development of dual-affinity avidins, enabling the adjustment of ligand binding properties in different binding sites. Additionally, he has developed a single-chain avidin (scAvd) that combines two dcAvd molecules into a single polypeptide with four binding sites for biotin or other ligands. Another significant patent focuses on chimeric avidin mutants, which exhibit improved properties such as thermostability and better stability against proteolysis. These mutants incorporate regions from avidin-related proteins, enhancing their overall performance.
Career Highlights
Throughout his career, Kulomaa has worked with various companies, including Licentia Oy and Orion Diagnostica Oy. His experience in these organizations has contributed to his expertise in the field of biochemistry and protein engineering.
Collaborations
Kulomaa has collaborated with notable colleagues, including Vesa Pekka Hytönen and Olli Heikki Laitinen. These partnerships have fostered innovation and the exchange of ideas in their research endeavors.
Conclusion
Markku Sakari Kulomaa's contributions to the field of biochemistry through his patents on avidin proteins demonstrate his innovative spirit and dedication to advancing scientific knowledge. His work has the potential to influence various applications in biotechnology and beyond.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile