This inventor holds 1 USPTO granted patent. Top assignee: The University of North Carolina at Chapel Hill. Active years: 2006.
Company Filing History:
Years Active: 2006
Title: Mark T Heise: Innovator in Alphavirus Vector Technology
Introduction
Mark T Heise is a prominent inventor based in Durham, NC (US). He is known for his significant contributions to the field of virology, particularly in the development of alphavirus vectors. His work has implications for therapeutic applications, especially in delivering genetic material to target cells.
Latest Patents
Mark T Heise holds a patent for "Vectors derived from South African Arbovirus No. 86." This patent includes alphavirus vectors derived from South African Arbovirus No. 86 (S.A.AR86) that comprise attenuating mutations and methods of making the same. The invention also encompasses improved viral vectors and helper constructs that include a S.A.AR86 capsid enhancer sequence. Furthermore, it provides methods for administering an alphavirus vector that carries a heterologous nucleotide sequence, which is particularly useful for targeting cells in the bone and bone-associated connective tissue.
Career Highlights
Heise is affiliated with the University of North Carolina at Chapel Hill, where he has been instrumental in advancing research in viral vector technology. His innovative approaches have paved the way for new therapeutic strategies in medicine.
Collaborations
Some of his notable coworkers include Robert E Johnston and Dennis Simpson, who have collaborated with him on various research projects.
Conclusion
Mark T Heise's work in the field of alphavirus vectors represents a significant advancement in biotechnology. His contributions continue to influence the development of novel therapeutic approaches.