Mark Selby

Title: Mark Selby: Innovator in Genetic Engineering

Introduction

Mark Selby is a prominent inventor based in San Francisco, CA. He has made significant contributions to the field of genetic engineering, particularly in the development of modified B cells for therapeutic applications. His innovative work aims to address various diseases and disorders, showcasing the potential of genetic modifications in medicine.

Latest Patents

Mark Selby holds a patent for "Modified B cells and methods of use thereof." This invention relates to genetically modified B cells that can be utilized for the treatment of a variety of diseases, including cancer, heart disease, inflammatory diseases, muscle wasting diseases, and neurological disorders. The patent describes an isolated modified B cell, known as a CAR-B cell, which is capable of expressing a chimeric receptor. This chimeric receptor includes an extracellular domain, a transmembrane domain, and a cytoplasmic domain that comprises at least one signaling domain. The invention also encompasses modified B cells that can express and secrete a payload, such as an antibody or its fragment, which is not naturally expressed in a B cell or is expressed at higher levels than normally found.

Career Highlights

Mark Selby is currently associated with Walking Fish Therapeutics, where he continues to advance his research in genetic modifications. His work is pivotal in exploring new therapeutic avenues that leverage the capabilities of modified B cells. With a focus on innovative solutions, Selby is at the forefront of developing treatments that could significantly impact patient care.

Collaborations

Mark collaborates with talented individuals in his field, including Kathleen Boyle and Hangil Park. Their combined expertise contributes to the success of their projects and enhances the research environment at Walking Fish Therapeutics.

Conclusion

Mark Selby is a key figure in the realm of genetic engineering, with a focus on modified B cells that hold promise for treating various diseases. His innovative patent and ongoing work at Walking Fish Therapeutics highlight the potential of genetic modifications in advancing medical treatments.