Location History:
- Encinitas, CA (US) (2003)
- San Diego, CA (US) (2001 - 2014)
Company Filing History:
3 out of 15,471 
2 out of 64 
1 out of 832,812 Years Active: 2001-2014
Title: **Mark Roman: Innovator in Immunology and Oligonucleotide Therapies**
Introduction
Mark Roman is an accomplished inventor based in San Diego, California, known for his contributions to the field of immunology and oligonucleotide-based therapies. With a portfolio of five patents, his innovations focus on harnessing the potential of oligonucleotides to treat autoimmune diseases and immunomodulate responses.
Latest Patents
One of Mark Roman's most significant patents is titled "Use of Inhibitory Oligonucleotides to Treat Autoimmune Disease." This invention includes oligonucleotides that inhibit the immunostimulatory activity of immunostimulatory sequence oligodeoxynucleotides (ISS-ODN). The methods described allow for the identification and application of these oligonucleotides in controlling both therapeutic and undesired ISS-ODN activity, particularly in the context of gene therapy and gene immunization.
Another notable patent is for "Immunostimulatory Polynucleotide/Immunomodulatory Molecule Conjugates." This invention concerns compositions where a polynucleotide is linked to an immunomodulatory molecule, including antigens and additional immunomodulators such as cytokines and adjuvants. The methods outlined offer strategies for modulating immune responses when these conjugates are administered to vertebrate hosts.
Career Highlights
Mark has had an impressive career, contributing his expertise to renowned institutions such as the University of California and Dynavax Technologies Corporation. His work in these organizations has solidified his reputation as a leading inventor in the realm of immunology.
Collaborations
Throughout his professional journey, Mark Roman has collaborated with esteemed colleagues Eyal Raz and Dennis A Carson. Their combined expertise has furthered advancements in the understanding of immune responses and therapeutic applications of oligonucleotides.
Conclusion
In summary, Mark Roman stands out as an innovative force in the field of immunology, with key inventions aimed at addressing autoimmune diseases through the use of oligonucleotides. With a solid track record of patents and collaborations, his work continues to influence the development of cutting-edge therapies in modern medicine.