The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2003

Filed:

Apr. 22, 1999
Applicant:
Inventors:

Eyal Raz, Del Mar, CA (US);

Mark Roman, Encinitas, CA (US);

Dino Dina, Oakland, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 4/304 ; C12Q 1/68 ; C12N 1/588 ; C07H 2/102 ; A61K 3/800 ;
U.S. Cl.
CPC ...
A01N 4/304 ; C12Q 1/68 ; C12N 1/588 ; C07H 2/102 ; A61K 3/800 ;
Abstract

The invention relates to immunostimulatory oligonucleotide compositions. These oligonucleotides comprise an immunostimulatory octanucleotide sequence. These oligonucleotides can be administered in conjunction with an immunostimulatory peptide or antigen. Methods for modulating an immune response upon administration of the oligonucleotide are also disclosed. In addition, an in vitro screening method to identify oligonucleotides with immunostimulatory activity is provided.


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