Location History:
- San Jose, CA (US) (2019 - 2021)
- San Diego, CA (US) (2021 - 2023)
Company Filing History:
Years Active: 2019-2025
Title: Innovations of Mark R. Ambroso in Nanopore Technology
Introduction
Mark R. Ambroso is an accomplished inventor based in San Jose, California, recognized for his significant contributions to the field of nanopore technology. With a remarkable portfolio of six patents, he has been at the forefront of developing innovative solutions that enhance the efficiency and accuracy of DNA sequencing processes.
Latest Patents
One of his latest patents focuses on "Long Lifetime Alpha-Hemolysin Nanopores." This invention describes variants of alpha-hemolysin featuring at least one amino acid substitution at specific positions such as H35G, E111N, M113A, and/or K147N within the wild-type alpha-hemolysin amino acid sequence. These variants also include other substitutions that optimize their functionality. The new alpha-hemolysin variants are designed to improve both the longevity of nanopore assemblies as well as decrease the time required for threading DNA molecules through the nanopores. This advancement not only enhances the lifespan of the nanopores but also significantly improves the efficiency and accuracy of DNA sequencing reactions.
Career Highlights
Mark R. Ambroso currently works at Roche Sequencing Solutions, Inc., a leading company in the field of genomic sequencing technology. His work is vital in addressing the growing needs of rapid and accurate DNA sequencing, contributing to various applications in medical research and diagnostics.
Collaborations
Throughout his career, Mark has collaborated with talented coworkers such as Timothy Kellogg Craig and Corissa Harris. These collaborations have been instrumental in fostering innovation and promoting advancements in nanopore technologies.
Conclusion
Mark R. Ambroso's inventive contributions to the field of nanopore technology showcase his dedication to enhancing scientific research methods. His patented innovations, particularly in the realm of alpha-hemolysin variants, reflect a commitment to pushing the boundaries of genomic sequencing and improving the tools available to researchers worldwide. Through his work at Roche Sequencing Solutions, Inc., he continues to lead efforts in revolutionizing how DNA sequencing is performed, paving the way for further breakthroughs in molecular biology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.