This inventor holds 3 USPTO granted patents and 2 published patent applications and 2 EPO patents. Top assignees: Alexion Pharmaceuticals, Inc., Fortis Life Sciences. Active years: 2023-2026.
Company Filing History:
Years Active: 2023-2026
Title: Mark Ma: Innovator in Complement Protein Quantitation
Introduction
Mark Ma is a notable inventor based in Madison, CT (US). He has made significant contributions to the field of biochemistry, particularly in the quantitation of complement proteins. With a total of 3 patents, his work has implications for both research and clinical applications.
Latest Patents
Mark Ma's latest patents include innovative methods for quantitating unbound complement proteins. The first patent details a method for quantitating free (unbound) human C5 complement protein. This method involves binding biotinylated anti-C5 capture antibody to streptavidin-coated particles, capturing the free C5 in the sample, detecting the captured free C5, and quantitating it using laser-induced fluorescence detection. This process is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument.
The second patent focuses on a similar approach for quantitating free (unbound) human C5a complement protein. This method also involves binding biotinylated anti-C5a capture antibody to streptavidin-coated particles, capturing the free C5a, detecting it, and quantitating it using laser-induced fluorescence detection. Notably, human C5 is first removed from the sample before this process is conducted.
Career Highlights
Mark Ma is currently employed at Alexion Pharmaceuticals, Inc., where he continues to advance his research in complement proteins. His work is crucial for understanding various biological processes and developing therapeutic strategies.
Collaborations
Throughout his career, Mark has collaborated with notable colleagues, including Mark Dysinger and Bruce A Andrien, Jr. These collaborations have further enriched his research and contributed to the success of his innovative methods.
Conclusion
Mark Ma's contributions to the field of complement protein quantitation highlight his role as an influential inventor. His patents reflect a commitment to advancing scientific knowledge and improving clinical practices.