The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
Oct. 19, 2017
Applicant:
Alexion Pharmaceuticals, Inc., Boston, MA (US);
Inventors:
Mark Dysinger, Killingworth, CT (US);
Mark Ma, Madison, CT (US);
Assignee:
Alexion Pharmaceuticals, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/564 (2006.01); G01N 33/543 (2006.01); C07K 16/36 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); C07K 16/36 (2013.01); G01N 33/54326 (2013.01); G01N 33/54366 (2013.01);
Abstract
A method of quantitating free (unbound) human C5a complement protein (C5a) from a sample comprising: binding biotinylated anti-C5a capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5a; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument; wherein human C5 is first removed from the sample.