Location History:
- Newton, MA (US) (2002 - 2003)
- Boxford, MA (US) (2003 - 2007)
Company Filing History:
4 out of 5 
1 out of 832,880 Years Active: 2002-2007
Title: Mark J Pykett: Innovator in Hematopoietic Progenitor Cell Research
Introduction
Mark J Pykett is a notable inventor based in Boxford, MA (US). He has made significant contributions to the field of hematopoietic progenitor cell research, holding a total of 5 patents. His work focuses on innovative methods for cell production and culture, which have implications for medical research and therapies.
Latest Patents
One of his latest patents is titled "Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices." This invention describes a method for producing lymphoid tissue-specific cells from hematopoietic progenitor cells using unique three-dimensional culture devices. The process occurs in the presence of antigen-presenting cells and lymphoreticular stromal cells, without the need for exogenously added growth factors. The resulting cells can be isolated at various stages of differentiation and can be genetically altered throughout the process.
Another significant patent is "Methods and devices for the long-term culture of hematopoietic progenitor cells." This invention pertains to the long-term in vitro culture of hematopoietic progenitor cells without the addition of exogenous growth factors. It also includes improved methods for introducing foreign genetic material into hematopoietic cells. The use of a three-dimensional porous biomaterial enhances cell survival and functionality while maintaining pluripotency.
Career Highlights
Mark J Pykett has worked with Cytomatrix, LLC, where he has applied his expertise in cell culture and genetic engineering. His innovative approaches have contributed to advancements in the field of regenerative medicine.
Collaborations
Throughout his career, Mark has collaborated with notable individuals such as Michael Rosenzweig and Richard B Kaplan. These collaborations have further enriched his research and development efforts.
Conclusion
Mark J Pykett is a distinguished inventor whose work in hematopoietic progenitor cell research has led to significant advancements in cell production and culture methods. His contributions continue to impact the field of medical research and therapy development.