The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2007
Filed:
May. 31, 2002
Mark J. Pykett, Boxford, MA (US);
Michael Rosenzweig, Boston, MA (US);
David T. Scadden, Weston, MA (US);
Mark C. Poznansky, Charlestown, MA (US);
Mark J. Pykett, Boxford, MA (US);
Michael Rosenzweig, Boston, MA (US);
David T. Scadden, Weston, MA (US);
Mark C. Poznansky, Charlestown, MA (US);
Cytomatrix, LLC, Chelmsford, MA (US);
Abstract
The invention relates to a method for lymphoid tissue-specific cell production from hematopoietic progenitor cells in unique, three-dimensional culture devices, in the presence of antigen presenting cells and lymphoreticular stromal cells, and in the absence of exogenously added growth factors. The resulting lymphoid tissue-specific cells may be isolated at any sequential stage of differentiation and further expanded. The lymphoid tissue-specific cells also may be genetically altered at any stage of the process.