Inventors with similar research interests:
Location History:
- San Clem, CA (US) (2009)
- Carlsbad, CA (US) (2011 - 2014)
- San Clemente, CA (US) (2001 - 2023)
Company Filing History:
40 out of 1,035 
21 out of 271 
5 out of 789 
Years Active: 2001-2025
Areas of Expertise:
Title: Mark J Graham - A Pioneer in Apolipoprotein Research
Introduction
Mark J Graham is a distinguished inventor and researcher based in San Clemente, CA, with an impressive portfolio of 65 patents to his name. His innovative work primarily focuses on compositions and methods for modulating apolipoprotein (a) expression, contributing significantly to the fields of medicine and biotechnology.
Latest Patents
Mark’s latest patents include the development of oligomeric compounds designed to target apolipoprotein (a) [apo(a)], which plays a vital role in various medical conditions. One notable patent describes how these oligomeric compounds can be conjugated to N-Acetylgalactosamine, providing a novel approach for decreasing apo(a) levels. This work aims to treat, prevent, or ameliorate diseases related to apo(a) and Lp(a), including inflammatory, cardiovascular, and metabolic disorders. Additionally, he has developed antisense compounds and methods for decreasing apo(a), maintaining his focus on treating conditions associated with this vital protein.
Career Highlights
Throughout his career, Mark has made substantial contributions to biotechnology while working at renowned organizations such as Isis Pharmaceuticals, Inc. and Ionis Pharmaceuticals, Inc. His expertise and innovative approach have positioned him as a key player in the development of therapies aimed at cardiovascular and metabolic diseases.
Collaborations
Mark J Graham has collaborated with prominent professionals in the field, including Rosanne M Crooke and Susan M Freier. These partnerships have fostered a collaborative environment that enhances the potential of their research and the impact on health innovations.
Conclusion
Mark J Graham's dedication to advancing medical science through innovation underscores the significance of his contributions in the field of apolipoprotein research. With an extensive patent portfolio and a commitment to improving health outcomes, he continues to be an influential figure in the biotechnology landscape.