Location History:
- Silver Spring, MD (US) (2011 - 2012)
- Washington, DC (US) (2013 - 2022)
Company Filing History:
5 out of 3,440 
1 out of 33 Years Active: 2011-2022
Title: Innovations in Cancer Treatment: The Contributions of Mark E Dudley
Introduction
Mark E Dudley, an esteemed inventor based in Washington, DC, has made significant strides in the field of cancer treatment through his innovative approaches. With a total of five patents to his name, Dudley has focused on enhancing the efficiency of cancer therapies, particularly through the use of tumor infiltrating lymphocytes (TIL) and T cell methodologies.
Latest Patents
Dudley's two latest patents exemplify his groundbreaking work in immunotherapy. The first patent details "Methods of growing tumor infiltrating lymphocytes in gas-permeable containers." This method involves obtaining tumor tissue samples from mammals, culturing them in gas-permeable containers, extracting TIL, and subsequently expanding them using irradiated allogeneic or autologous feeder cells. Ultimately, these expanded TIL are administered back to the mammal to promote cancer regression.
The second patent, titled "Adoptive cell therapy with young T cells," outlines a procedure to enhance cancer treatment outcomes. It includes culturing and expanding autologous T cells, administering nonmyeloablative lymphodepleting chemotherapy, and then reintroducing expanded T cells that are approximately 19 to 35 days old. This innovative approach aims to promote significant regression of cancer in treated mammals.
Career Highlights
Throughout his career, Mark E Dudley has contributed his expertise to prominent organizations, including the United States of America as represented by the Secretary of the Department of Health and Human Services and Wilson Wolf Manufacturing Corporation. His work has been pivotal in advancing the methodologies underlying modern cancer treatments.
Collaborations
In his journey, Dudley has collaborated with notable peers, including Steven A Rosenberg and John R Wunderlich. This collaborative environment has fostered a shared vision of improving cancer therapies and advancing medical science.
Conclusion
Mark E Dudley's innovative work not only showcases his dedication to combating cancer, but also exemplifies the transformative power of research and collaboration in developing effective treatments. His patents represent a significant step forward in the field of immunotherapy, offering hope for improved outcomes in cancer care.