Company Filing History:
Years Active: 2019-2025
Title: Innovations of Mark C Wallen
Introduction
Mark C Wallen is a notable inventor based in San Diego, California. He has made significant contributions to the field of biotechnology, particularly in the stabilization of nucleic acid-nucleotide-polymerase complexes. With a total of four patents to his name, Wallen's work has implications for various applications in genetic research and molecular biology.
Latest Patents
Wallen's latest patents focus on methods and compositions for stabilizing nucleic acid-nucleotide-polymerase complexes. These patents describe methods, compositions, kits, and apparatuses that include a fluid containing a ternary complex and lithium (Li). The ternary complex consists of a primed template nucleic acid, a polymerase, and a nucleotide cognate for the next correct base for the primed template nucleic acid molecule. As an alternative or addition to Li, the fluid can contain betaine or a metal ion that inhibits polymerase catalysis, such as calcium (Ca). Furthermore, the fluid may also include polyethylenimine (PEI) with or without betaine.
Career Highlights
Throughout his career, Wallen has worked with prominent companies in the biotechnology sector, including Omniome, Inc. and Pacific Biosciences of California, Inc. His experience in these organizations has allowed him to develop innovative solutions that enhance the efficiency and effectiveness of nucleic acid manipulation.
Collaborations
Wallen has collaborated with talented individuals in his field, including Pinar Iyidogan and Ying Lin Liu. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Mark C Wallen's contributions to biotechnology through his patents and collaborations highlight his role as an influential inventor in the field. His work continues to pave the way for advancements in genetic research and molecular biology.