Company Filing History:
Years Active: 1988-1989
Title: Mark B Frank: Innovator in Monoclonal Antibody Technology
Introduction
Mark B Frank is a notable inventor based in Irvine, CA, who has made significant contributions to the field of biotechnology. He holds 2 patents that focus on the development of monoclonal antibodies for DNA-RNA hybrid complexes. His work is pivotal in advancing techniques for detecting specific nucleic acid sequences.
Latest Patents
Frank's latest patents include innovative methods for utilizing monoclonal antibodies that can distinguish DNA-RNA hybrid complexes from single-stranded and double-stranded DNA and RNA. These antibodies are particularly useful for determining the presence of specific nucleic acid sequences on solid surfaces. The process involves fixing a single-stranded polynucleotide to a solid gel surface, hybridizing it with a complementary probe, and then adding the hybrid complex-specific monoclonal antibody. This allows for the visualization of hybrid complexes through various labeling techniques.
Career Highlights
Mark B Frank is affiliated with the University of Hawai'i, where he continues to contribute to research and development in his field. His work has implications for various applications in molecular biology and diagnostics.
Collaborations
Frank collaborates with W Dorsey Stuart, enhancing the research efforts in monoclonal antibody technology.
Conclusion
Mark B Frank's innovative work in monoclonal antibodies represents a significant advancement in biotechnology, particularly in the detection of nucleic acid sequences. His contributions continue to influence the field and pave the way for future research and applications.