Mark Arthur Findeis

Title: Innovator Spotlight: Mark Arthur Findeis

Introduction

Mark Arthur Findeis, based in Belmont, MA, is a notable inventor with a total of 14 patents to his name. His work largely focuses on advancements in the field of immunology, particularly through the development of antibodies that play critical roles in cancer treatment. Findeis's innovations highlight the intersection of biotechnology and therapeutic applications, showcasing his significant contributions to this vital area of research.

Latest Patents

Two of Findeis's most recent patents are groundbreaking in the realm of cancer therapy. The first patent, titled "Anti-CTLA-4 antibodies and methods of use thereof," encompasses antibodies that specifically bind to CTLA-4, including human CTLA-4, and effectively antagonize its function. This disclosure includes pharmaceutical compositions, nucleic acids encoding these antibodies, expression vectors, and host cells designed for their production, alongside methods for treating patients using these antibodies.

His second patent, "Antibodies and methods of use thereof," extends the application of his innovations to include antibodies that target both CTLA-4 and PD-1, antagonizing their functions as well. This patent also details the development of pharmaceutical compositions and kits that contain these antibodies, as well as the necessary nucleic acids and methods for patient treatment.

Career Highlights

Throughout his career, Mark Arthur Findeis has made significant contributions through positions at prominent organizations such as Agenus Inc. and the Ludwig Institute for Cancer Research Limited. His efforts in these companies have played a crucial role in advancing therapeutic strategies aimed at modifying immune responses against tumors.

Collaborations

Findeis has worked alongside respected colleagues, including Marc A Van Dijk and Cornelia Anne Mundt. These collaborations have likely contributed to the richness and depth of his research, fostering an environment where innovative ideas can emerge and flourish.

Conclusion

Mark Arthur Findeis stands out as a pivotal figure in the field of biotechnology, with a strong focus on developing novel therapeutic solutions for cancer treatment. His patents not only reflect his expertise but also underscore the importance of innovation in improving patient outcomes. As research continues to evolve, Findeis’s work exemplifies the ongoing quest for effective cancer therapies.