Mark A Blenner

Title: Mark A Blenner: Innovator in Peptide Engineering

Introduction

Mark A Blenner is a notable inventor based in Clemson, SC (US). He has made significant contributions to the field of peptide engineering, particularly in the development of calcium-dependent hydrogels. With a total of 2 patents, his work has implications in various scientific and medical applications.

Latest Patents

One of Mark A Blenner's latest patents is focused on "Leucine beta roll domains and uses thereof." This invention relates to a peptide that forms a calcium-dependent hydrogel using a rationally engineered beta roll peptide. In the absence of calcium, the peptide is intrinsically disordered. Upon the addition of calcium, the peptide forms a corkscrew-like structure. In one embodiment, one face of the beta roll is mutated to comprise leucine residues. In some embodiments, a leucine zipper forming helical domain to the engineered beta roll forms hydrogels by physical cross-linking in calcium-rich environments.

Career Highlights

Mark A Blenner is affiliated with Columbia University, where he continues to advance his research in peptide engineering. His innovative work has garnered attention in the scientific community, contributing to the understanding of peptide behavior in various environments.

Collaborations

Throughout his career, Mark has collaborated with esteemed colleagues such as Scott Banta and Ian R Wheeldon. These collaborations have further enriched his research and expanded the impact of his inventions.

Conclusion

Mark A Blenner is a prominent figure in the field of peptide engineering, with innovative patents that showcase his expertise. His contributions to the development of calcium-dependent hydrogels highlight the potential applications of his work in science and medicine.