Company Filing History:
9 out of 2,597 
1 out of 3,923 
Years Active: 2010-2019
Title: The Innovative Contributions of Mariusz Wasik
Introduction
Mariusz Wasik, based in Ardmore, PA, is a notable inventor with a remarkable portfolio comprising nine patents. His inventions are primarily focused on advancements in cancer treatment, particularly through innovative methods and compositions aimed at addressing complex malignancies.
Latest Patents
One of Mariusz Wasik's latest patents involves the treatment of cancer using anti-CD19 Chimeric Antigen Receptor. This invention provides compositions and methods for treating diseases associated with the expression of CD19 by administering a recombinant T cell that comprises the CD19 CAR, in combination with a kinase inhibitor. Additionally, the invention includes kits and compositions designed to enhance the efficacy of these treatments.
Another significant patent addresses the role of STAT5a and its functional tumor suppressor analogs in treating malignancies expressing NPM/ALK and other oncogenic kinases. This invention outlines methods to inhibit epigenetic gene silencing in cells that express NPM/ALK by using agents that increase the concentration of Stat5a protein or its functional analogs. Furthermore, it introduces methods for diagnosing malignancies related to these oncogenic kinases and monitoring patient responses to therapy by analyzing the degree of DNA methylation of the gene encoding Stat5a or its analogs.
Career Highlights
Throughout his career, Mariusz Wasik has contributed significantly to the fields of biomedical research and innovation. He has had the privilege of working with esteemed organizations such as the University of Pennsylvania and Novartis AG, where he honed his skills and expanded his knowledge in drug discovery and cancer therapies.
Collaborations
Mariusz Wasik has collaborated with notable professionals in the field, including Leslie M. Shaw and Qian Zhang. These collaborations have undoubtedly enriched his research endeavors and contributed to the development of impactful solutions in cancer treatment.
Conclusion
Mariusz Wasik's contributions to the field of cancer treatment through his innovative patents illustrate his commitment to advancing medical science. His work not only reflects his ingenuity as an inventor but also positions him as a key player in the ongoing battle against cancer. As research continues to evolve, the implications of his inventions hold the promise of enhancing patient outcomes and transforming therapeutic strategies.