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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9255279 B1

PDFFull Text
Date of Patent:
Feb. 09, 2016

Filed:

Mar. 05, 2014

Anaplastic lymphoma kinase (alk) as an oncogene capable of transforming normal human cells

Applicant:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

Mariusz Wasik, Ardmore, PA (US);

James L. Riley, Downingtown, PA (US);

Qian Zhang, Philadelphia, PA (US);

Fang Wei, Drexel Hill, PA (US);

Assignee:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Attorneys:

Saul Ewing LLP

Kathryn Doyle

Primary Examiner:

Doug Schultz

Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01); C12N 15/85 (2006.01); G01N 33/50 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); G01N 33/5011 (2013.01); A01K 2207/12 (2013.01); A01K 2267/0331 (2013.01); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01); G01N 2333/91205 (2013.01);
Abstract

The present invention provides compositions and methods for transforming primary mammalian cells using an oncogenic form of ALK wherein the transformed cells display features of that of a corresponding tumor cell isolated from a cancer subject. The invention also provides a method for immortalizing normal CD4+ T lymphocytes with a lymphoma-characteristic form of ALK such as NPM-ALK.

Find Patent Forward Citations

Wasik, Mariusz. (2016). Anaplastic lymphoma kinase (alk) as an oncogene capable of transforming normal human cells (U.S. Patent No. 9255279). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9255279

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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