Company Filing History:
Years Active: 2016-2019
Title: Innovations of Qian Zhang in Cancer Treatment
Introduction
Qian Zhang is a prominent inventor based in Philadelphia, PA, known for his significant contributions to the field of cancer treatment. He has been awarded 3 patents for his innovative work, particularly focusing on the role of STAT5a in malignancies.
Latest Patents
One of Qian Zhang's latest patents involves the use of STAT5a and its functional tumor suppressor analogs for the treatment of malignancies expressing NPM/ALK and other oncogenic kinases. This invention provides methods for inhibiting epigenetic gene silencing in cells expressing NPM/ALK. It also details how to decrease NPM/ALK content in a cell by using agents that increase the concentration of Stat5a protein or its functional analog. Furthermore, the invention outlines a method for treating malignancies by administering agents that enhance the concentration of Stat5a protein or its epigenetically silenced functional tumor suppressor analog in malignant cells. Additionally, it offers a diagnostic method to monitor a patient's response to therapy by analyzing the degree of DNA methylation of the gene encoding for Stat5a or its analog, as well as their mRNA or protein.
Career Highlights
Qian Zhang is affiliated with the University of Pennsylvania, where he continues to advance research in cancer therapies. His work has garnered attention for its potential to improve treatment outcomes for patients with specific malignancies.
Collaborations
He collaborates with notable colleagues, including Mariusz Wasik and James L. Riley, who contribute to the research and development of innovative cancer treatments.
Conclusion
Qian Zhang's innovative work in the field of cancer treatment exemplifies the impact of research on improving patient care. His patents reflect a commitment to advancing medical science and enhancing therapeutic options for malignancies.