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For the Inventor, By the Inventor

Marlborough, MA, United States of America

Mariusz Krawiec

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This inventor holds 31 USPTO granted patents and 22 published patent applications, plus 7 CIPO patents and 13 EPO patents, primarily in Pharmaceutical Chemistry. Top assignee: Vertex Pharmaceuticals, Inc.. Active years: 2013-2024.

USPTO Granted Patents = 31 

% Patents Active = 93.5


 

Average Co-Inventor Count = 4.3

ph-index = 23

Forward Citations = 1,489(Granted Patents)


Company Filing History:

goldMedal31 out of 1,167 
 
Vertex Pharmaceuticals, Inc.
 patents

Years Active: 2013-2024

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Areas of Expertise:
Pharmaceutical Chemistry
Solid Forms
Cyclopropanecarboxamide
Gyrase Inhibitors
Benzoic Acid
Fluoro Compounds
Dihydroquinoline
Quinoline
Indole Derivatives
Carboxamide
Hydroxyphenyl
Dimethylethyl
31 patents (USPTO):Explore Patents
1. 12065432 - Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid (2024-08-20),
2. 11578062 - Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (2023-02-14),
3. 11291662 - Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (2022-04-05),
4. 10906891 - Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (2021-02-02),
5. 10597384 - Solid forms of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid (2020-03-24),
6. 10537565 - Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (2020-01-21),
7. 10081621 - Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (2018-09-25),
8. 9931334 - Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (2018-04-03),
9. 9840499 - Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid (2017-12-12),
10. 9670163 - Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (2017-06-06),
11. 9434717 - Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid (2016-09-06),
12. 9314455 - Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (2016-04-19),
13. 9150552 - Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid (2015-10-06),
14. 9139530 - Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (2015-09-22),
15. 9051303 - [object Object] (2015-06-09),

Title: Mariusz Krawiec: Innovator in Pharmaceutical Chemistry

Introduction

Mariusz Krawiec, based in Marlborough, Massachusetts, is an accomplished inventor with a significant portfolio of 31 patents. His contributions primarily focus on innovative pharmaceutical compounds and formulations, reflecting his dedication to advancing medicinal chemistry.

Latest Patents

Mariusz Krawiec's recent patented innovations include:

1. **Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid** - This invention pertains to a substantially crystalline and free solid-state form of the compound, along with pharmaceutical compositions and methods for treatment.

2. **Solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide** - This patent describes solid forms in substantially crystalline form or amorphous form, complete with pharmaceutical compositions and treatment methodologies.

Career Highlights

Mariusz has demonstrated his expertise while working at prominent companies such as Vertex Pharmaceuticals, Inc. and Vertex Pharmaceuticals Incorporated. His focus on developing novel pharmaceutical solutions has likely contributed to better treatment options in the industry.

Collaborations

Throughout his career, Mariusz Krawiec has collaborated with talented professionals, including Beili Zhang and Ali Keshavarz-Shokri. These collaborations have undoubtedly enhanced innovation and research within the pharmaceutical field.

Conclusion

Mariusz Krawiec stands out as a key innovator in the field of pharmaceutical chemistry, with a rich array of patents that push the boundaries of medicinal development. His work continues to make significant strides in providing better therapeutic options, demonstrating the importance of innovation in healthcare.

Profile summary based on public USPTO records.
Please report any incorrect information to [email protected]
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