The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2023
Filed:
Nov. 25, 2020
Applicant:
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Inventors:
Ali Keshavarz-Shokri, San Diego, CA (US);
Beili Zhang, San Diego, CA (US);
Tim Edward Alcacio, San Diego, CA (US);
Elaine Chungmin Lee, Arlington, MA (US);
Yuegang Zhang, Wayland, MA (US);
Mariusz Krawiec, Marlborough, MA (US);
Assignee:
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); A61K 31/404 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61K 31/404 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 45/06 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith.