Company Filing History:
Years Active: 2005-2012
Title: Innovations and Contributions of Mario N Lioubin
Introduction
Mario N Lioubin is a notable inventor based in San Mateo, California. He has made significant contributions to the field of biotechnology, particularly in the study of the p53 pathway and its implications for cancer therapy. With a total of two patents to his name, Lioubin's work focuses on identifying therapeutic targets for disorders associated with defective p53 function.
Latest Patents
Lioubin's latest patents include groundbreaking research on "Marks as modifiers of the p53 pathway and methods of use." This patent identifies human MARK genes as modulators of the p53 pathway, presenting them as potential therapeutic targets for various disorders. Additionally, he has developed methods for identifying modulators of p53, which involve screening for agents that can influence the activity of MARK. His second patent, "Human RRP sequences and methods of use," involves Rhomboid Related Proteins (RRPs) that play a crucial role in the EGFR signaling pathway. This patent outlines transgenic, nonhuman mammals containing a transgene encoding an RRP polypeptide, along with methods for modulating the interaction of RRP proteins with their pathway members.
Career Highlights
Lioubin is currently employed at Exelixis, Inc., a company known for its focus on developing innovative cancer therapies. His work at Exelixis has allowed him to contribute to significant advancements in the understanding of cancer biology and therapeutic interventions.
Collaborations
Throughout his career, Lioubin has collaborated with esteemed colleagues such as Lori Friedman and Marcia Belvin. These collaborations have further enriched his research and contributed to the success of his projects.
Conclusion
Mario N Lioubin's innovative work in biotechnology, particularly regarding the p53 pathway and RRP proteins, showcases his commitment to advancing cancer research. His patents reflect a deep understanding of molecular biology and its potential applications in therapeutic development.