The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2012

Filed:

Jun. 10, 2010
Applicants:

Lori Friedman, San Carlos, CA (US);

Gregory D. Plowman, San Carlos, CA (US);

Helen Francis-lang, San Francisco, CA (US);

Danxi LI, San Francisco, CA (US);

Roel P. Funke, South San Francisco, CA (US);

Marcia Belvin, Albany, CA (US);

Mario N. Lioubin, San Mateo, CA (US);

Inventors:

Lori Friedman, San Carlos, CA (US);

Gregory D. Plowman, San Carlos, CA (US);

Helen Francis-Lang, San Francisco, CA (US);

Danxi Li, San Francisco, CA (US);

Roel P. Funke, South San Francisco, CA (US);

Marcia Belvin, Albany, CA (US);

Mario N. Lioubin, San Mateo, CA (US);

Assignee:

Exelixis, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/574 (2006.01); C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Human MARK genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of MARK are provided.


Find Patent Forward Citations

Loading…