Company Filing History:
Years Active: 1991-1994
Title: Marina Del Bue: Innovator in Biotechnology
Introduction
Marina Del Bue is a prominent inventor based in Milan, Italy. She has made significant contributions to the field of biotechnology, particularly in the development of plasmid vectors for protein expression. With a total of 2 patents, her work has implications in pharmaceuticals and food production.
Latest Patents
Marina's latest patents include a plasmid vector for expression in Bacillus, which is used for cloning the structural gene that codes for human growth hormone. This invention involves a recombinant DNA molecule that comprises the plasmid vector and the structural gene of the human growth hormone. The method of preparing the hormone includes inserting the recombinant DNA molecule into strains of Bacillus and cultivating the resulting transformed strains in a suitable culture environment. The synthesized hormone is then recovered from the cells.
Another notable patent is a cloning vector that is useful for the expression and secretion of heterologous proteins in Bacillus subtilis. This invention describes molecules of recombinant DNA formed by the cloning vector, which is cut at a restriction site located within the neutral protease gene. The Bacillus subtilis cells transformed with these molecules are capable of expressing the sequence of heterologous DNA and producing high yields of the protein coded by that sequence. The proteins obtained through this method are valuable in pharmaceuticals and food production.
Career Highlights
Marina Del Bue is currently employed at Eniricerche S.p.a., where she continues to advance her research in biotechnology. Her innovative work has positioned her as a key figure in her field, contributing to the development of new biotechnological solutions.
Collaborations
Throughout her career, Marina has collaborated with notable colleagues such as Guido Grandi and Salvatore Toma. These partnerships have enhanced her research and expanded the impact of her inventions.
Conclusion
Marina Del Bue is a trailblazer in the biotechnology sector, with her patents paving the way for advancements in protein expression and cloning technologies. Her contributions are essential for the future of pharmaceuticals and food production.