Frederick, MD, United States of America

Marina A Dobrovolskaia

USPTO Granted Patents = 1 

Average Co-Inventor Count = 7.0

ph-index = 1


Company Filing History:


Years Active: 2022

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1 patent (USPTO):Explore Patents

Title: Marina A. Dobrovolskaia: Innovator in Nucleic Acid Nanoparticles

Introduction

Marina A. Dobrovolskaia is a prominent inventor based in Frederick, MD (US). She has made significant contributions to the field of molecular biology, particularly in the development of nucleic acid nanoparticles. Her innovative work has led to the creation of a unique molecular switch that has potential applications in various biomedical fields.

Latest Patents

Marina A. Dobrovolskaia holds one patent titled "Functionally-interdependent shape switching nucleic acid nanoparticles." This patent describes a molecular switch comprising at least two nanoparticles. The first nanoparticle contains DNA and/or RNA oligonucleotides, while the second nanoparticle, which is complementary to the first, comprises reverse complementary DNA and/or RNA oligonucleotides. These complementary nanoparticles interact under physiological conditions, resulting in thermodynamically driven conformational changes that lead to their re-association. This process releases one or more duplexes containing the specified oligonucleotides, showcasing a novel approach to nanoparticle design.

Career Highlights

Throughout her career, Marina has worked with esteemed organizations such as the National Institutes of Health, a component of the US Department of Health & Human Services, and the University of North Carolina at Charlotte. Her experience in these institutions has allowed her to advance her research and contribute to the scientific community significantly.

Collaborations

Marina has collaborated with notable colleagues, including Bruce Allen Shapiro and Kirill Andreevich Afonin. These partnerships have fostered a collaborative environment that enhances innovation and research in her field.

Conclusion

Marina A. Dobrovolskaia is a trailblazer in the realm of nucleic acid nanoparticles, with her patent reflecting her innovative spirit and dedication to advancing molecular biology. Her work continues to inspire future research and development in this critical area of science.

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