Tsukuba, Japan

Mariko Umemura


Average Co-Inventor Count = 4.8

ph-index = 1


Location History:

  • Ibaraki, JP (2010)
  • Tsukuba, JP (2012)

Company Filing History:


Years Active: 2010-2012

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2 patents (USPTO):Explore Patents

Title: Mariko Umemura: Innovator in Antifungal Research

Introduction

Mariko Umemura is a prominent inventor based in Tsukuba, Japan. She has made significant contributions to the field of antifungal research, holding a total of 2 patents. Her work focuses on innovative methods for screening compounds that can inhibit fungal growth and improve treatment options.

Latest Patents

One of her latest patents is titled "Method of screening for compounds that inhibit the enzymatic activity of GWT1 gene product." This invention enables the screening of compounds that inhibit the transport of GPI-anchored proteins to fungal cell walls. The method utilizes a simple assay for transacylation to GlcN-PI using membrane fractions expressing the GWT1 protein. This innovation has the potential to lead to the development of new antifungal agents that can inhibit the synthesis of fungal cell walls and prevent adhesion to host cells.

Another significant patent by Umemura is "Lipid remodeling of GPI-anchored proteins." This invention provides insights into the proteins and genes involved in the GPI lipid remodeling process. It also establishes a system for screening useful substances, such as anticancer agents, and for detecting abnormalities in the GPI lipid remodeling process.

Career Highlights

Mariko Umemura has worked with esteemed organizations, including the National Institute of Advanced Industrial Science and Technology and Eisai R&D Management Co., Ltd. Her experience in these institutions has allowed her to contribute to groundbreaking research in her field.

Collaborations

Throughout her career, Umemura has collaborated with notable colleagues, including Yoshifumi Jigami and Takehiko Yoko-O. These partnerships have further enhanced her research and innovation efforts.

Conclusion

Mariko Umemura is a distinguished inventor whose work in antifungal research has the potential to revolutionize treatment options. Her patents reflect her commitment to advancing scientific knowledge and improving health outcomes.

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