Marie Tosolini

Title: Marie Tosolini: Innovator in Cancer Research

Introduction

Marie Tosolini is a prominent inventor based in Toulouse, France. She has made significant contributions to the field of cancer research, particularly in the development of targeted therapies. Her innovative work focuses on antibodies that target tumor-associated macrophages, which play a crucial role in tumor progression.

Latest Patents

Marie Tosolini holds a patent for "Antibodies targeting tumor associated macrophages and uses thereof." This invention relates to antibodies that specifically target Tumor Associated Macrophages (TAMs). The research conducted by Tosolini and her team identified a specific marker on the surface of macrophages associated with tumors, allowing for the detection and targeting of TAMs. They discovered that sideroflexin 3, which is absent in normal macrophages, is expressed by tumor-associated macrophages. The team demonstrated that by using antibodies directed at sideroflexin 3, they could deplete TAMs in PBMC samples obtained from leukemia patients, significantly reducing the number of leukemic B cells.

Career Highlights

Throughout her career, Marie has worked with esteemed institutions such as the Institut National de la Santé et de la Recherche Médicale and Université Paul Sabatier Toulouse. Her research has been pivotal in advancing the understanding of tumor biology and developing new therapeutic strategies.

Collaborations

Marie has collaborated with notable colleagues, including Mary Poupot and Loïc Ysebaert. Their combined expertise has contributed to the success of her research endeavors.

Conclusion

Marie Tosolini is a trailblazer in the field of cancer research, with her innovative work on antibodies targeting tumor-associated macrophages paving the way for new therapeutic approaches. Her contributions continue to impact the scientific community and offer hope for improved cancer treatments.