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Years Active: 2016
Title: Biography of Inventor Mariana Pehar
Introduction: Mariana Pehar is an accomplished inventor based in Middleton, Wisconsin. She has made significant contributions to the field of neurobiology through her innovative research and patents. Her work focuses on the post-translational modifications of neurotrophins and their implications in chronic pain and neuron loss.
Latest Patents: Mariana holds a patent for "Post-translationally modified neurotrophin antibodies." This invention describes how neurotrophins undergo post-translational modifications that mediate their pro-apoptotic and pro-neurite activities. Notably, these modifications include nitration and the formation of conformationally different dimers, as well as abnormal oligomers such as tetramers and octamers. The invention also relates to compounds that compete with these modified neurotrophins, providing useful agents for treating conditions involving chronic pain and neuron loss.
Career Highlights: Throughout her career, Mariana has worked with prestigious institutions, including Institut Pasteur and Instituto de Investigaciones Biologicas Clemente Estable. Her research has garnered attention for its potential applications in therapeutic settings.
Collaborations: Mariana has collaborated with notable colleagues, including Luis Barbeito and Patricia Cassina. These partnerships have enriched her research and contributed to the advancement of knowledge in her field.
Conclusion: Mariana Pehar is a pioneering inventor whose work on
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