Cambridge, United Kingdom

Marian Hanlon


Average Co-Inventor Count = 6.7

ph-index = 2

Forward Citations = 32(Granted Patents)


Company Filing History:


Years Active: 2007-2009

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3 patents (USPTO):Explore Patents

Title: Marian Hanlon: Innovator in Protein Engineering

Introduction

Marian Hanlon is a distinguished inventor based in Cambridge, GB. She has made significant contributions to the field of protein engineering, particularly in the development of artificial proteins with reduced immunogenicity. With a total of 3 patents to her name, her work has the potential to impact therapeutic applications significantly.

Latest Patents

One of her latest patents focuses on artificial proteins with reduced immunogenicity. This invention relates to modified proteins, especially fusion proteins, that exhibit lower immunogenicity compared to their non-modified counterparts when exposed to a species in vivo. The invention emphasizes novel immunoglobulin fusion proteins that consist of an immunoglobulin molecule or a fragment covalently fused to a biologically active non-immunoglobulin molecule. The aim is to create fusion proteins that maintain the same biological activity as the non-altered molecules while reducing immune reactions.

Another notable patent involves fusion proteins of interferon alpha muteins with improved properties. This invention concerns modified forms of interferon alpha 2 that contain amino acid substitutions at specific positions, enhancing their relative activity in biological assays. These improved proteins are designed for therapeutic use, targeting diseases in humans while minimizing immunogenic potential.

Career Highlights

Marian Hanlon is currently associated with Merck Patent GmbH, where she continues to innovate in the field of protein engineering. Her work has garnered attention for its potential applications in medicine and biotechnology.

Collaborations

Marian collaborates with notable colleagues, including Matthew Baker and Francis Joseph Carr, contributing to a dynamic research environment that fosters innovation.

Conclusion

Marian Hanlon's contributions to the field of protein engineering exemplify the impact of innovative thinking in biotechnology. Her patents reflect a commitment to advancing therapeutic solutions through scientific research and collaboration.

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