The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
Feb. 18, 2004
Tim Jones, Babraham, GB;
Matthew Baker, Horningsea, GB;
Marian Hanlon, Cambridge, GB;
Francis Joseph Carr, Balmedie, GB;
Tim Jones, Babraham, GB;
Matthew Baker, Horningsea, GB;
Marian Hanlon, Cambridge, GB;
Francis Joseph Carr, Balmedie, GB;
Merck Patent GmbH, Darmstadt, DE;
Abstract
The invention concerns human interferon alpha and in particular modified forms of interferon alpha 2 with improved properties. The improved proteins contain amino acid substitutions at specific positions that confer increased relative activity in biological assays. The invention provides also modified interferon alpha with improved biological activity concomitant with reduced immunogenic potential in the protein. The improved proteins are intended for therapeutic use in the treatment of diseases in humans.