This inventor holds 1 USPTO granted patent and 1 published patent application and 1 EPO patent. Top assignees: Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Conicet), Fundacion Instituto Leloir. Active years: 2013.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 81 
1 out of 5 Years Active: 2013
Title: Maria Veronica Lopez: Innovator in Tumor Gene Expression
Introduction
Maria Veronica Lopez is a prominent inventor based in La Plata, Argentina. She has made significant contributions to the field of genetic engineering, particularly in the area of tumor biology. Her innovative work focuses on the use of isolated DNA fragments to drive gene expression in tumor cells.
Latest Patents
Maria Veronica Lopez holds a patent for an isolated DNA fragment of the SPARC human promoter and its application in driving the expression of heterologous genes in tumor cells. This patent describes a DNA sequence that corresponds to a region of the SPARC gene human promoter, specifically from base pair -513 to base pair +35. This sequence is capable of driving the expression of a heterologous gene of interest, which can be linked to various promoter sequences, including radiation-responsive, hypoxia-responsive, and free-radical-responsive sequences. The invention also encompasses constructs and DNA recombinant expression viral vectors that include the isolated SPARC gene human promoter sequence and at least one heterologous gene operably linked to it. The promoter sequence effectively drives the expression of the heterologous gene in tumor cells. Additionally, the patent provides pharmaceutical compositions and methods for treating tumors.
Career Highlights
Throughout her career, Maria Veronica Lopez has worked with esteemed organizations such as the National Scientific and Technical Research Council (CONICET) and the Leloir Institute Foundation. Her research has significantly advanced the understanding of gene expression in cancer therapy.
Collaborations
Maria has collaborated with notable colleagues, including Osvaldo Podhajcer and Eduardo Gustavo Alfredo Cafferata. Their joint efforts have contributed to the development of innovative solutions in the field of tumor treatment.
Conclusion
Maria Veronica Lopez is a trailblazer in the field of genetic engineering, with her patent on the SPARC human promoter showcasing her innovative approach to cancer treatment. Her work continues to inspire advancements in tumor biology and gene therapy.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile