Maria Paula Carranza Sandmeier

Title: Maria Paula Carranza Sandmeier: Innovator in Bioconjugate Technology

Introduction

Maria Paula Carranza Sandmeier is an accomplished inventor based in Rudolfstetten, Switzerland, known for her pioneering work in the field of bioconjugate technology. With four patents to her name, her research contributes significantly to advancements in the development of vaccines against extra-intestinal pathogenic Escherichia coli (ExPEC).

Latest Patents

Her latest patents focus on methods of producing bioconjugates of O-antigen polysaccharides, which are crucial in the development of effective vaccine candidates. The patents describe innovative methods utilizing recombinant host cells that express specific oligosaccharyl transferase enzymes, facilitating the production of bioconjugates that can be used to vaccinate subjects against harmful pathogens. Two notable patents detail the production of glucosylated O4 antigen polysaccharides linked to carrier proteins, highlighting the potential for these bioconjugates to induce specific antibody responses.

Career Highlights

Throughout her career, Maria has made significant strides in her field by working with renowned organizations, including Janssen Pharmaceuticals, Inc. and GlaxoSmithKline Biologicals SA. Her contributions have improved the understanding of bioconjugate applications in vaccines and have established her as a knowledgeable figure in pharmaceutical innovation.

Collaborations

Maria has collaborated with prominent researchers in her field, including Jeroen Geurtsen and Pieter Jan Burghout. These collaborative efforts have allowed her to leverage diverse expertise, driving innovation and refining methodologies associated with bioconjugate production.

Conclusion

Maria Paula Carranza Sandmeier stands out as a dedicated inventor, making notable contributions to the field of bioconjugate technology. Her innovative patents and collaborations reflect a commitment to solving complex health challenges, particularly in vaccine development. As the landscape of pharmaceuticals continues to evolve, her work serves as a testament to the vital role inventors play in advancing public health.