Maria Nieddu

Title: Maria Nieddu - Innovator in Pharmaceutical Chemistry

Introduction

Maria Nieddu is an accomplished inventor based in Sassari, Italy. She has made significant contributions to the field of pharmaceutical chemistry, where her innovative approaches aim to improve drug efficacy and safety. Her work is particularly focused on non-steroidal anti-inflammatory drugs (NSAIDs), an area critical to medicine given the widespread use of these medications.

Latest Patents

Maria Nieddu holds a patent for "Galactosylated pro-drugs of non-steroidal anti-inflammatories with improved pharmacokinetic characteristics and reduced toxicity of the starting drug." This patent covers pro-drugs of all NSAIDs characterized by a free acid function that are derivatized with an ester group. The structural formula includes various NSAIDs such as aspirin, diclofenac, ibuprofen, and naproxen. The creativity in her invention lies in the incorporation of sugar moieties, which can include a wide range of sugars and their derivatives, enhancing the pharmacological profile of these medications.

Career Highlights

Throughout her career, Maria has been associated with Stewart Italia Srl, among other companies, where she has applied her expertise in drug development. Her singular patent underscores her innovative capabilities and her dedication to advancing pharmaceutical chemistry.

Collaborations

Maria has collaborated with notable colleagues, including Maria Grazia Rimoli and Antonio Calignano. These collaborations have likely contributed to her successful patent and her overall contributions to the field of medicinal chemistry.

Conclusion

Maria Nieddu is a pioneering inventor whose work in the development of galactosylated pro-drugs represents a significant advancement in the pharmaceutical industry. Her passion for improving the efficacy and safety of medications is evident in her innovative patent, positioning her as a noteworthy figure in the realm of drug development.