Company Filing History:
Years Active: 2007
Title: Maria Magdalena Flocco: Innovator in Biochemical Screening
Introduction
Maria Magdalena Flocco is a distinguished inventor based in Milan, Italy. She has made significant contributions to the field of biochemical screening, particularly through her innovative patent related to Fluorine NMR spectroscopy. Her work is pivotal in the drug-lead discovery process, emphasizing the importance of quality in functional assays.
Latest Patents
Maria Magdalena Flocco holds a patent for a method that utilizes Fluorine NMR spectroscopy for high-throughput screening of large compound libraries. This method enhances the screening of Ser/Thr kinases and requires the presence of a CF moiety on the substrate. The technique allows for real-time experiments or endpoint assay formats, using protein and substrate concentrations similar to those employed by other high-throughput screening techniques. The application of this method to the phosphorylation of a substrate by the protein Ser/Thr kinase AKT1 showcases its effectiveness.
Career Highlights
Flocco is currently associated with Pfizer Italia S.r.l., where she continues to advance her research and innovations. Her work has been recognized for its impact on the pharmaceutical industry, particularly in the realm of drug discovery and development.
Collaborations
Throughout her career, Maria has collaborated with notable colleagues, including Claudio Dalvit and Elena Ardini. These partnerships have further enriched her research and contributed to the success of her projects.
Conclusion
Maria Magdalena Flocco is a remarkable inventor whose work in biochemical screening has the potential to transform drug discovery processes. Her innovative approach and dedication to quality in research continue to inspire advancements in the field.