Location History:
- Lakewood, CO (US) (1999 - 2014)
- Golden, CO (US) (2014)
Company Filing History:
3 out of 508 
2 out of 278 
1 out of 1 Years Active: 1999-2014
Title: Maria Lucia Ghirardi: Pioneering Innovations in Hydrogenase Research
Introduction
Maria Lucia Ghirardi is an accomplished inventor based in Lakewood, Colorado, with a remarkable portfolio consisting of six patents. Her work primarily focuses on the field of hydrogenase research, contributing significantly to advancements in sustainable energy solutions.
Latest Patents
Among her latest patents, Ghirardi has developed a process for the expression and overexpression of active [FeFe] hydrogenases. This innovative process allows for the efficient cloning and transfer of necessary genes into host organisms that lack the native [FeFe]-hydrogenases. By culturing these organisms aerobically and inducing anaerobiosis, she facilitates the biosynthesis of [FeFe] hydrogenases and subsequent hydrogen production.
Another notable patent involves oxygen-resistant iron-hydrogenases. Ghirardi's work elucidates the design and engineering of these hydrogenases, which are crucial for producing hydrogen efficiently. The methods she has devised enable the transformation and culturing of appropriate host cells to utilize these oxygen-resistant variants in bulk hydrogen production, leveraging light-catalyzed reactions with water.
Career Highlights
Maria Lucia Ghirardi has made significant contributions while working at organizations such as Alliance for Sustainable Energy, LLC and Midwest Research Institute. Her expertise in hydrogenase system design has been instrumental in advancing technologies aimed at improving energy sustainability.
Collaborations
Throughout her illustrious career, Ghirardi has collaborated with notable professionals, including Michael Seibert and Paul W. King. Their collective efforts have enriched the research landscape in hydrogen biology and energy production.
Conclusion
Maria Lucia Ghirardi stands out as a leading inventor in hydrogenase research. Her innovative patents and collaborations pave the way for advancements in sustainable energy solutions, underlining her significant impact on the scientific community and the future of clean energy technologies.