Maria D Cebezas

Title: Maria D Cebezas: Innovator in Cellular Assays and Nanopatterned Extracellular Matrices

Introduction

Maria D Cebezas is a prominent inventor based in Evanston, IL (US). She has made significant contributions to the field of cellular assays and mass spectrometry. With a total of 2 patents, her work focuses on innovative methods that enhance the capabilities of high-throughput screening and enzyme activity measurement.

Latest Patents

Cebezas's latest patents include groundbreaking technologies. The first patent, titled "Cellular assays with a molecular endpoint measured by SAMDI mass spectrometry," provides a cell-based, label-free assay compatible with high-throughput screening (HTS). This method quantitatively reports on enzyme activities by measuring mass changes of substrates using MALDI-mass spectrometry. The second patent, "Nanopatterned extracellular matrices enable cell-based assays with a mass spectrometric readout," outlines methods where adherent cells are treated with small molecules, cultured, lysed, and analyzed by mass spectrometry to measure the activities of endogenous enzymes. This innovative approach relies on nanopatterned surfaces that facilitate cell attachment and enzyme activity measurement.

Career Highlights

Maria D Cebezas is affiliated with Northwestern University, where she continues to advance her research and contribute to the scientific community. Her work has garnered attention for its potential applications in various fields, including drug discovery and biomedical research.

Collaborations

Cebezas has collaborated with notable researchers, including Milan Mrksich and Chad A Mirkin. These partnerships have further enriched her research and expanded the impact of her inventions.

Conclusion

Maria D Cebezas is a trailblazer in the realm of cellular assays and nanopatterned technologies. Her innovative patents and collaborations highlight her commitment to advancing scientific knowledge and improving methodologies in enzyme activity measurement.