Margit Foss

Title: Margit Foss: Innovator in Replication Complex Genes

Introduction

Margit Foss is a notable inventor based in Durham, NC (US). She has made significant contributions to the field of molecular biology, particularly in the study of origin of replication complex (ORC) genes. With a total of 2 patents, her work has implications for understanding and treating diseases associated with undesirable cell growth.

Latest Patents

Margit Foss's latest patents focus on the Origin of Replication Complex (ORC) genes. These patents include nucleic acids that encode ORC proteins and hybridization reagents, probes, and primers capable of hybridizing with ORC genes. The methods outlined in her patents provide a framework for screening chemical libraries for lead compounds that may serve as pharmacological agents. These agents are useful in the diagnosis or treatment of diseases linked to undesirable cell growth. An exemplary screening method involves forming a mixture that includes a recombinant ORC protein, a natural intracellular ORC protein binding target, and a candidate pharmacological agent. The mixture is incubated under specific conditions to detect the binding of the ORC protein to the target.

Career Highlights

Throughout her career, Margit Foss has worked with prestigious institutions such as Cold Spring Harbor Laboratory and the University of California. Her research has significantly advanced the understanding of replication processes at the molecular level.

Collaborations

Margit has collaborated with esteemed colleagues, including Bruce W. Stillman and Stephen P. Bell. These collaborations have further enriched her research and contributed to the scientific community's knowledge of ORC genes.

Conclusion

Margit Foss is a pioneering inventor whose work on ORC genes has the potential to impact the diagnosis and treatment of various diseases. Her contributions to molecular biology continue to inspire future research in the field.