Margaret S Lee

This inventor holds 9 USPTO granted patents and 5 published patent applications and 1 EPO patent. Top assignees: Praxis Precision Medicines, Inc., Cavion, Inc., Biogen Ma Inc.. Active years: 2010-2026.

USPTO Granted Patents = 9 (Patent Applications = 5)

% Patents Active = 77.8

EPO Patents = 1 (Patent Applications = 4)

Average Co-Inventor Count = 3.5

ph-index = 3

Forward Citations = 20(Granted Patents)

Location History:

Irvington, NJ (US) (2010)
Middleton, MA (US) (2010 - 2024)

Company Filing History:

3 out of 35

Praxis Precision Medicines, Inc.

Combinatorx, Incorporated

patents

5. 2 out of 834,411

Other

patents

Years Active: 2010-2026

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9 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12528772 - Formulations of T-type calcium channel modulators and methods of use thereof (2026-01-20),

2. 12383539 - Treating essential tremor using (R)-2-(4-Isopropylphenyl)-N-(1-(5-(2,2,2-Trifluoroethoxy)pyridin-2-yl)ethyl)acetamide (2025-08-12),

3. 12077502 - Formulations of T-type calcium channel modulators and methods of use thereof (2024-09-03),

4. 11602530 - CRM1 inhibitors for treating epilepsy (2023-03-14),

5. 11427540 - Formulations of T-type calcium channel modulators and methods of use thereof (2022-08-30),

6. 11311522 - Treating essential tremor using (R)-2-(4-Isopropylphenyl)-N-(1-(5-(2,2,2-trifluoroethoxy)pyridin-2-yl)ethyl)acetamide (2022-04-26),

7. 11236078 - Heterocyclic inhibitors of the sodium channel (2022-02-01),

8. 7795310 - Methods and reagents for the treatment of metabolic disorders (2010-09-14),

9. 7722593 - Disposable thong underwear (2010-05-25),

Title: The Innovative Contributions of Margaret S. Lee

Introduction

Margaret S. Lee is a prominent inventor based in Middleton, Massachusetts, known for her extensive contributions to the field of medical research and innovation. With a remarkable portfolio of seven patents, Lee has made significant strides in the understanding and treatment of neurological conditions, particularly those related to calcium channel modulation.

Latest Patents

Among her latest innovations, Lee has developed formulations of T-type calcium channel modulators and methods for their use. These formulations are crucial in preventing and treating diseases associated with aberrant T-type calcium channel functions, such as epilepsy and its various syndromes, essential tremors, and mood disorders. Alongside this, her patent on CRM1 inhibitors offers promising methods for treating epilepsy by utilizing nuclear transport modulators that can significantly reduce the severity and occurrence of seizures in affected subjects.

Career Highlights

Lee's career is marked by her roles in various reputable companies, including Praxis Precision Medicines, Inc. Her work is characterized by a dedication to advancing therapeutic options for patients with neurological disorders. Her innovative thinking and commitment to research have positioned her as a valuable contributor in her field.

Collaborations

Throughout her career, Margaret has collaborated with many talented individuals, including notable coworkers such as Kiran Reddy and Gabriel Maurice Belfort. These partnerships have facilitated the development of groundbreaking approaches in neuroscience and pharmacology, further enhancing the potential impact of her inventions.

Conclusion

Margaret S. Lee's inventions and patents illustrate her significant impact on medical science, particularly in the areas of epilepsy and mental health. Her innovative work continues to pave the way for new treatment methods, representing a profound commitment to improving the quality of life for individuals facing challenging medical conditions.