The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2024

Filed:

Jul. 22, 2022
Applicant:

Praxis Precision Medicines, Inc., Boston, MA (US);

Inventors:

Kiran Reddy, Boston, MA (US);

Margaret S. Lee, Middleton, MA (US);

Gabriel Maurice Belfort, Cambridge, MA (US);

Sapna Makhija Garad, Malden, MA (US);

Mahesh Padval, Cambridge, MA (US);

Randall Wagner, Bend, OR (US);

Marion Wittmann, Medford, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/34 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 31/445 (2006.01); A61K 47/38 (2006.01); A61P 25/14 (2006.01); C07D 211/26 (2006.01);
U.S. Cl.
CPC ...
C07D 211/34 (2013.01); A61K 9/0053 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/4825 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01); A61K 31/445 (2013.01); A61K 47/38 (2013.01); A61P 25/14 (2018.01); C07D 211/26 (2013.01); C07B 2200/13 (2013.01);
Abstract

Described herein, in part, are dosage forms and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a T-type calcium channel, such as epilepsy and epilepsy syndromes (e.g., absence seizures, juvenile myoclonic epilepsy, or a genetic epilepsy), tremor (e.g., essential tremor), and psychiatric disorder (e.g., mood disorders (e.g., major depressive disorder)). The present invention further comprises methods for modulating the function of a T-type calcium channel.


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